Narumi Uno, et al. (2023) Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency. Nucleic Acid V33: 391-403
Teppei Sunaguch, et al. (2023) High Glucose-stimulated aPKC Activation Promotes Pancreatic Cancer Cell Progression Through YAP Signailng. ANITICANCER RESEARCH V43: 4843-4853
Hitomaru Miyamoto, et al. (2024) Rapid human genomic DNA cloning into mouse artificial chromosome via direct chromosome transfer from human iPSC and CRISPR/Cas9-mediated translocation Nucleic Acids Research 1-14
Chiye Sakurai, et al. (2024) VAMP5 promotes Fcγ receptor-mediated phagocytosis and regulates phagosome maturation in mactophages. Molecular Biology fo the Cell V35(44): 1-15
2022年度 4件
Hiroyuki Satofuka, et al. (2022). Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci. Nature Communications 13:1841(2022), doi:0.1038/s41467-022-29421-2
Tatsuyuki Kurashiki, et al. (2022). Molecular mechanisms underlying the promotion of wound repair by coenzyme Q10: PI3K/Akt signal activation via alterations to cell membrane domains. J Clin Biochem Nutr. 2022 May;70(3):222-230. doi: 10.3164/jcbn.21-141
Satoshi Koba, et al. (2022). A brainstem monosynaptic excitatory pathway that drives locomotor activities and sympathetic cardiovascular responses. Nature Communications 13:5079(2022), doi:10.1038/s41467-022-32823-x
2021年度 4件
Taiji Miyake, et al. (2021). Predicting quantitatively P-glycoprotein mediated drug-drug interactions and intestinal absorption using humanized mice.British Journal of Pharmacology 2021 Jul 7. doi: 10.1111/bph.15612
Takahito Ohira, et al. (2021). PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes. Scientific Reports. 2021 11:18405
Takuya Ikenari, et al. (2021). Improvement in Double Staining With Fluoro-Jade C and Fluorescent Immunostaining: FJC Staining Is Not Specific to Degenerating Mature Neurons. Journal of Histochemistry & Cytochemistry 2021 Sep;69(9):597-610
Yasuhiro Kazuki, et al. (2022). A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features. The American Journal of Human Genetics 2022 Feb;109:1-17
2020年度 5件
Koba, S; Hanai, E; Kumada, N; Watanabe, T. (2020). Sympathoexcitatory input from hypothalamic paraventricular nucleus neurons projecting to rostral ventrolateral medulla is enhanced after myocardial infarction. American Journal of Physiology-Heart and Circulatory Physiology, DOI: 10.1152/ajpheart.00273.2020
Narai, T; Watase, R; Nakayama, Y; et al. (2020). Establishment of human immortalized mesenchymal stem cells lines for the monitoring and analysis of osteogenic differentiation in living cells. Heliyon, DOI: 10.1016/j.heliyon.2020.e05398
Kazuki, Y; Gao, F. J; Li, Y; et al.. (2020). A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21. ELife, DOI: 10.7554/eLife.56223
Baba, T; Miyazaki, D; Inata, K; et al. (2020). Role of il-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration. ELife, DOI: 10.7554/eLife.54257
Ohira, T; Kojima, H; Kuroda, Y; et al. (2019). PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription. PLOS ONE, DOI: 10.1371/journal.pone.0217605
2019年度 7件
Ohira, T; Miyauchi, K; Uno, N; et al. (2019). An efficient protein production system viα gene amplification on a human artificial chrosome and the chromosome transfer to CHO cells. SCIENTIFIC REPORTS, DOI: 10.1038/s41598-019-53116-2
Ozuru, R; Wakao, S; Tsuji, T; et al. (2019). Rescue from Stx2-Producing E. coli-Associated Encephalopathy by Intravenous Injection of Muse Cells in NOD-SCID Mice. Molecular Therapy, DOI: 10.1016/j.ymthe.2019.09.023
Kinoshita, D; Sakurai, C; Morita, M; et al. (2019). Syntaxin 11 regulates the stimulus-dependent transport of Toll-like receptor 4 to the plasma membrane by cooperating with SNP-23 in macrophages. Molecular Biology of the Cell, DOI: 10.1091/mbc.E18-10-0653
Hiramatsu, K; Abe, S; Kazuki, K; et al. (2019). Generation of a novel isogenic trisomy panel in human embryonic stem cells via microcell-mediated chromosome transfer. Biochemical and Biophysical Research Communications, DOI: 10.1016/j.bbrc.2018.11.138
Li, Y; Kokura, K; & Inoue, T. (2019). Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression. Biochemical and Biophysical Research Communications, DOI: 10.1016/j.bbrc.2018.11.136
Kazuki, Y; Kobayashi, K; Hirabayashi, M; et al. (2019). Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America, DOI:10.1073/pnas.1808255116
2018年度 3件
Koba, S; Hanai, E; Kumada, N; et al. (2018). Sympathoexcitation by hypothalamic paraventricular nucleus neurons projecting to the rostral ventrolateral medulla. Journal of Physiology, DOI: 10.1113/JP276223
Saito, K; Koike, T; Kawashima, F; et al. (2018). Identification of NeuN immunopositive cells in the adult mouse subventricular zone. Journal of Comparative Neurology, DOI: 10.1002/cne.24463a
Sakurai, C; Itakura, M; Kinoshita, D; et al. (2018). Phosphorylation of SNAP^23 at Ser95 causes a structural alteration and negatively regulates Fc receptor-mediated phagosome formation and maturation in macrophages. Molecular Biology of the Cell, DOI: 10.1091/mbc.E17-08-0523
2017年度 5件
Horikoshi, Y; Kamizaki, K; Hanaki, T; et al. (2017). α-Tocopherol promotes HaCaT karatinocyte wound repair through the regulation of polarity proteins leading to the polarized cell migration. BioFactors, DOI: 10.1002/biof.1414
Satoh, D; Iwado, S; Abe, S; et al. (2017). Establishment of a novel hepatocyte model that expresses four cytochrome P450 genes stably via mammalian-derived artificial chromosome for pharmacokinetics and toxicity studies. PLoS ONE, DOI: 10.1371/journal.pone.0187072
Abe, S; Kobayashi, K; Oji, A; et al. (2017). Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology. Scientific Reports, DOI: 10.1038/s41598-017-15033-0
Kawashima, F; Saito, K; Kurata,H; et al. (2017). c-jun is differentially expressed in embryonic and adult neural precursor cells. Histochemistry and Cell Biology, DOI: 10.1007/s00418-016-1536-2
