About Tottori Bio Frontier

Message from professor, Dr. Oshimura

We have developed the chromosome engineering technology for drug discovery and healthcare industries

We have built up world-leading chromosome engineering technology over three decades while investigating cancer suppressing genes and creating complete human antibody-producing mice. We are now attempting to apply this technology to various industrial fields while utilizing the expertise we developed during that process.
We intend to use the benefits of human/mouse artificial chromosomes to achieve results that were not possible with previous gene vectors. Moreover, We feel that we must conduct collaborative research with various pharmaceutical and healthcare-related companies to successfully apply our technologies to drug discovery and genetic and regenerative medicine. We are open to any consultation, from which we can begin with the planning stage.

Mitsuo Oshimura

Professor, Tottori University
Chromosome Engineering Research Center
Research Supervisor, Bio Frontier Promotion Office,
Tottori Industrial Promotion Organization
Managing Director, Tottori Bioscience Organization
CEO, Trans Chromosomics Co.


  • FY 2006 to FY 2008
    Research Representative of the City Area Program,
    Ministry of Education, Culture, Sports, Science and Technology
  • FY 2010 to FY 2012
    Research Representative of the Regional Innovation Cluster Program,
    Ministry of Education, Culture, Sports, Science and Technology
  • FY 2011 to the present
    Development of a globally pioneering toxicity test method required for new chemical regulations for petroleum refinery substances and other substances for the Ministry of Economy, Trade and Industry
    (Development of techniques for testing hepatotoxicity, nephrotoxicity, and neurotoxicity in vitro) Topic Leader
  • FY 2013 to the present
    Research Director, Regional Innovation Strategy Support Program,
    Ministry of Education, Culture, Sports, Science and Technology

Major awards

  • 1993
    Princess Takamatsu Cancer Research Fund Prize
  • 1998
    Nikkei BP Medical and Biotechnology Prize
  • 2002
    Japan Society of Human Genetics Academic Award